Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Evening primrose oil United States Pharmacopeia (USP) Reference Standard | 308064-97-3 | 1G
Evening primrose oil United States Pharmacopeia (USP) Reference Standard | 308064-97-3 | 1G
Selleck Chemical LLC Onalespib (AT13387) S1163-5mg
Onalespib (AT13387) is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells displays a long duration of anti-tumor activity Phase 2
Medchemexpress LLC Lenalidomide-4-aminomethyl hydrochloride | 444289-05-8 | MFCD32703223 | 90.9% | 309.75 | C14H16ClN3O3 | 5 MG
Lenalidomide-4-aminomethyl hydrochloride is a lenalidomide-derived cereblon (CRBN) ligand used in chemical biology research and PROTAC design as an E3 ligase recruiting moiety. It is supplied as a hydrochloride salt solid, molecular weight 309.75, and chemical formula C14H16ClN3O3.
- Used as a CRBN ligand for targeted protein degradation studies.
- Suitable for PROTAC synthesis and linker conjugation.
- Provided as a hydrochloride salt for handling and stability.
- Characterized by RP-HPLC and LC-MS analytical methods.
- Offered in small research pack sizes for screening and optimization.
Medchemexpress LLC N-methyl-2-(pyridin-2-yl)-N-(2-(pyridin-2-yl)ethyl)ethanamine | 5452-87-9 | MFCD28157290 | 98.4% | 241.33 g/mol | C15H19N3 | 100 MG
Betahistine EP Impurity C is an analytical reference standard used for identification and quantification of a known impurity related to betahistine. The compound has molecular formula C15H19N3, molecular weight 241.33 g/mol, and a batch-reported purity of 98.38%. It is intended for method development, calibration, and impurity profiling in chromatographic and mass spectrometric assays.
- Analytical reference standard for impurity identification and quantification.
- Suitable for HPLC, GC, and MS method development.
- High reported purity (98.38%) for accurate calibrations.
- Defined molecular weight and formula to support analytical characterization.
- Provided in small-quantity packaging for laboratory use.
Medchemexpress LLC ARQ 621 | 1095253-39-6 | 98.09% | 552.43 | 1 MG
ARQ 621 is an allosteric, potent, and selective inhibitor of Eg5, which is a microtubule-based ATPase motor protein involved in cell division. It exhibits anti-tumor activity and functions as a kinesin inhibitor. Additionally, ARQ 621 is a click chemistry reagent, possessing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Allosteric, potent, and selective inhibitor of Eg5
- Targets microtubule-based ATPase motor protein involved in cell division
- Demonstrates anti-tumor activity
- Functions as a kinesin inhibitor
- Click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Selleck Chemical LLC Tandutinib (MLN518) 25mg 387867-13-2 CT 53518, NSC726292, MLN518
Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 ?M, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical Esomeprazole 500mg
An H+/K+-ATPase inhibitor; reversibly inhibits the activity of the H+/K+-ATPase in an enzyme assay; inhibits histamine-induced gastric acid secretion in rats at 30 mg/kg, s.c.
Medchemexpress LLC D-mannosamine hydrochloride | 5505-63-5 | MFCD00064557 | ≥98.0% | 215.63 | C6H14ClNO5 | 50 G
D-Mannosamine hydrochloride is an amino monosaccharide (an amino derivative of D-mannose) supplied as a solid research reagent. It is used in biochemical and cellular studies of carbohydrate metabolism, glycosylation, and cell-surface modification, and is provided with documentation for safe laboratory use.
- High purity (≥98.0%) suitable for biochemical and cellular assays.
- Solid, white to off-white form that is easy to handle and weigh.
- Used in studies of carbohydrate metabolism, glycosylation, and cell-surface modification.
- Supplied in multiple pack sizes to support small-scale and preparative experiments.
- Compatible with common aqueous solvents for solution preparation.
eMolecules 496775-62-3 | Eltrombopag Olamine | TargetMol | MFCD22380664 | 564.643 | C29H36N6O6 | 0.000 | NCCO.NCCO.CC1=NN(C(=O)\C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1 | 500mg | 819252854
Eltrombopag Olamine | TargetMol | 496775-62-3 | MFCD22380664 | 564.643 | C29H36N6O6 | 0.000 | NCCO.NCCO.CC1=NN(C(=O)\C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1 | 500mg | 819252854
Apexbio Technology LLC Desogestrel 54024-22-5 25mg
Desogestrel (CAS 54024-22-5) is a synthetic progestogen derivative targeting the progesterone receptor It is designed to selectively activate this receptor thereby suppressing gonadotropin secretion and inhibiting ovarian follicle maturation and ovulation Desogestrel exerts its biological activity primarily through selective activation of progesterone receptors Based on its chemical structure desogestrel contains an alkyne functional group that enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with azide-containing molecules Based on these pharmacological properties desogestrel holds research potential in targeted drug modification probe labeling and pharmacological investigations as well as serving as an active ingredient in oral contraceptive formulations
Medchemexpress LLC Neostigmine methyl sulfate | 51-60-5 | 98.9% | 5 MG
Neostigmine methyl sulfate (Standard) is the analytical standard of Neostigmine (methyl sulfate). This product is intended for research and analytical applications. It is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments.
- Used for research and analytical applications
- Reference standard supplied assay
- Commonly used in HPLC, GC and MS experiments
Apexbio Technology LLC Elacridar(Synonyms: GF120918, GG918, GW0918, GF-120918, GG-918, GW-0918), 100mg, CAS: 143664-11-3.
Elacridar (CAS 143664-11-3) is a potent inhibitor of P-glycoprotein (P-gp) a transmembrane efflux transporter belonging to the MDR/TAP subfamily P-gp actively exports diverse xenobiotics and drugs from cells significantly influencing drug bioavailability and distribution Elacridar inhibits P-gp with an IC50 of approximately 193 nM and markedly reduces transporter activity in P-gp-overexpressing MDCKII cell models at concentrations as low as 1 M In mice elacridar administration (10 mg/kg) enhances brain penetration of P-gp substrates such as sunitinib Thus elacridar is extensively used in biomedical research to study drug transport mechanisms and multidrug resistance
Sigma Aldrich Fine Chemicals Biosciences 2E,4E-Hexadienoic acid isobutylamide United States Pharmacopeia (USP) Reference Standard | 82240-09-3 | 25MG
2E,4E-Hexadienoic acid isobutylamide United States Pharmacopeia (USP) Reference Standard | Mol Wt: 167.25 | 82240-09-3 | 25MG
Medchemexpress LLC Folic acid disodium | 29704-76-5 | 98.6% | 485.36 | 100 MG
Folic acid disodium is an orally active disodium salt form of Folic acid. It serves as a cofactor in single-carbon transfer reactions. It demonstrates protective effects against neural tube defects, ischemic events, and cancer. Overload can lead to impaired brain development in embryogenesis and promote the growth of precancerous altered cells, while deficiency can result in megaloblastic anemia.
- Orally active disodium salt form of folic acid.
- Cofactor in single-carbon transfer reactions.
- Protects against neural tube defects, ischemic events, and cancer.
- Overload can impair brain development and promote precancerous altered cells.
- Deficiency can lead to megaloblastic anemia.
Selleck Chemical LLC Methotrexate S1210-500mg
Methotrexate analog of folic acid is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells It forms an inactive ternary complex with DHFR and NADPH Methotrexate (MTX) induces apoptosis